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Han LU

A Ph.D. in Neuroscience

I study the homeostatic structural plasticity of neuronal connectivity in response to external stimulation, with both computer simulations and in vivo or in vitro mouse experiments.

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Research Experience

Jülich Supercomputing Centre (JSC), Forschungszentrum Jülich GmbH, Germany

Researcher scientist • Apr, 2024 — now

Institute of Anatomy and Cell Biology, University of Freiburg, Germany

Postdoctoral researcher • Jan, 2021 — Dec, 2023

University of Strasbourg, France and University of Freiburg, Germany

Ph.D. thesis • Jun, 2017 — Oct, 2020

RIKEN CBS, Japan

RIKEN summer internship • Jun, 2018 — Aug, 2018

Klinik für Psychiatrie und Psychotherapie, Universitäts Klinikum Freiburg, Germany

Research Associate • Dec, 2016 — May, 2017

Bernstein Center Freiburg, University of Freiburg, Germany

Doing master thesis • Sep, 2015 — June, 2016

Klinik für Psychiatrie und Psychotherapie, Universitäts Klinikum Freiburg, Germany

Lab training on patch clamp • Jan, 2016

Education

University of Freiburg, Germany and University of Strasbourg, France

Ph.D. Degree, Neuroscience • June, 2017 — Oct, 2020

University of Strasbourg, France

Master Degree, Neuroscience • Sept, 2014 — July, 2016

Beijing Normal University, China

Bachelor Degree, Psychology • Sept, 2010 — July, 2014

Events and activities

BrainDisC PhD Conference

Co-organizer • Sep, 2017

Spiking Neuron Models Reading Club

Organizer • Apr, 2016 — March, 2017

Neural Network and Complex System Journal Club

Organizer • Aug, 2016 — April, 2017

Publications and Presentations

Lu H, Garg S, Lenz M, Vlachos A (2025) Repetitive magnetic stimulation with iTBS600 induces persistent structural and functional plasticity in mouse organotypic slice cultures. BioRxiv.

Lu H, Frase L, Normann C, Rotter S (2025) Resolving inconsistent effects of tDCS on learning using a homeostatic structural plasticity model. BioRxiv.

Cumming B, Yates S, Hater T, Lu H, Huisman B, Wouter K, Bösch F, Frasch S, de Schepper R, Luboeinski J (2024) Arbor v0.10.0 (v0.10.0). Zenodo.

Lu H, Diaz S, Lenz M, Vlachos A (2024) The interplay between homeostatic synaptic scaling and homeostatic structural plasticity maintains the robust firing rate of neural networks. elife.

Anil S, Lu H, Rotter S, Vlachos A (2023) Repetitive transcranial magnetic stimulation (rTMS) triggers dose-dependent homeostatic rewiring in recurrent neuronal networks. PLOS Computational Biology.

Shaner S, Lu H, Lenz M, Garg S, Vlachos A, Asplund M (2023) Brain stimulation-on-a-chip: a neuromodulation platform for brain slices. Lab on a Chip.

Lenz M, Eichler A, Kruse P, Stöhr P, Kleidonas D, Galanis C, Lu H, Vlachos A. Denervated mouse CA1 pyramidal neurons express homeostatic synaptic plasticity following entorhinal cortex lesion. Frontiers in Molecular Neuroscience. 2023 Apr 12;16:1148219.

Lu H, Shaner S, Otte E, Asplund M, Vlachos A (2023) A microfluidic perspective on conventional in vitro transcranial direct current stimulation methods. Journal of Neuroscience Methods 385.

Lu H, Gallinaro JV, Norman C, Rotter S, Yalcin I (2021) Time Course of Homeostatic Structural Plasticity in Response to Optogenetic Stimulation in Mouse Anterior Cingulate Cortex. Cerebral Cortex 32(8).

Lu H, Gallinaro JV, Rotter S (2019) Network remodeling induced by transcranial brain stimulation: A computational model of tDCS-triggered cell assembly formation. Network Neuroscience 3(4)

Lu H, Humo M, Yalcin I (2019) The molecular neurobiology of chronic pain–induced depression. Cell and Tissue Research 1-23.

Wang K, Lu H, Cheung EFC, Neuman DL, Shum DHK, Chan RCK (2016) Female preponderance of depression in non-clinical population: Evidence from a meta-analysis. Frontiers in Psychology 7.